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Human Protein Atlas tubb4a protein
The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.
Tubb4a Protein, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1) Product Images from "Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma"

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

Journal: Current Protein & Peptide Science

doi: 10.2174/1389201023666220928120902

The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.
Figure Legend Snippet: The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.

Techniques Used:

Univariate and Multivariate Cox analysis of 13 candidate genes.
Figure Legend Snippet: Univariate and Multivariate Cox analysis of 13 candidate genes.

Techniques Used:

Expression levels of DLL3 and TUBB4A ( A,B ),“*” represents “p-value < 0.05”;Disease Free Survival(DFS) ( C,D ); Progress Free Interval (PFI) ( E,F ); Disease Specific Survival (DSS) ( G,H ).
Figure Legend Snippet: Expression levels of DLL3 and TUBB4A ( A,B ),“*” represents “p-value < 0.05”;Disease Free Survival(DFS) ( C,D ); Progress Free Interval (PFI) ( E,F ); Disease Specific Survival (DSS) ( G,H ).

Techniques Used: Expressing, Significance Assay

Immunohistochemistry images of TUBB4A in SKCM tissues and normal skin tissues from Human Protein Atlas ( A ). The results of RT-qPCR of TUBB4A expression levels in skin cutaneous melanoma cell lines ( B ). ***, **, and * represent significant differences between skin cutaneous melanoma cell lines and human primary normal skin melanocytes, respectively (P<0.001, P<0.01, P<0.05).
Figure Legend Snippet: Immunohistochemistry images of TUBB4A in SKCM tissues and normal skin tissues from Human Protein Atlas ( A ). The results of RT-qPCR of TUBB4A expression levels in skin cutaneous melanoma cell lines ( B ). ***, **, and * represent significant differences between skin cutaneous melanoma cell lines and human primary normal skin melanocytes, respectively (P<0.001, P<0.01, P<0.05).

Techniques Used: Immunohistochemistry, Quantitative RT-PCR, Expressing

Prediction of miRNAs binding to  TUBB4A.
Figure Legend Snippet: Prediction of miRNAs binding to TUBB4A.

Techniques Used: Binding Assay

Upstream potential miRNAs predicted to bind to TUBB4A. The miRNA-TUBB4A network ( A ). Overall survival (OS) of miRNAs in TCGA-SKCM cohort ( B ). The expression of TUBB4A and hsa-let-7b-5p in SKCM was negatively correlated ( C ). The expression of TUBB4A and hsa-miR-423-5p in SKCM was positively correlated ( D ).
Figure Legend Snippet: Upstream potential miRNAs predicted to bind to TUBB4A. The miRNA-TUBB4A network ( A ). Overall survival (OS) of miRNAs in TCGA-SKCM cohort ( B ). The expression of TUBB4A and hsa-let-7b-5p in SKCM was negatively correlated ( C ). The expression of TUBB4A and hsa-miR-423-5p in SKCM was positively correlated ( D ).

Techniques Used: Expressing

The upstream lncRNAs of hsa-let-7b-5p in SKCM. The lncRNAs-hsa-let-7b-5p network ( A ). The expression levels of SNHG16 in skin cutaneous melanoma compared with TCGA normal and GTEx data controls ( B ), “*” represents “p-value < 0.05”. The expression of hsa-let-7b-5p and SNHG16 in SKCM was negatively correlated ( C ). The expression of TUBB4A and SNHG16 in SKCM was positively correlated ( D ).
Figure Legend Snippet: The upstream lncRNAs of hsa-let-7b-5p in SKCM. The lncRNAs-hsa-let-7b-5p network ( A ). The expression levels of SNHG16 in skin cutaneous melanoma compared with TCGA normal and GTEx data controls ( B ), “*” represents “p-value < 0.05”. The expression of hsa-let-7b-5p and SNHG16 in SKCM was negatively correlated ( C ). The expression of TUBB4A and SNHG16 in SKCM was positively correlated ( D ).

Techniques Used: Expressing, Significance Assay

The co-expressed genes of TUBB4A in SKCM through UALCAN and GEPIA database ( A ). The top 8 enriched in biological process (BP), cellular component (CC), molecular function (MF)items for the co-expressed genes of TUBB4A ( B ). The top 8 enriched in KEGG for the co-expressed genes of TUBB4A ( C ).
Figure Legend Snippet: The co-expressed genes of TUBB4A in SKCM through UALCAN and GEPIA database ( A ). The top 8 enriched in biological process (BP), cellular component (CC), molecular function (MF)items for the co-expressed genes of TUBB4A ( B ). The top 8 enriched in KEGG for the co-expressed genes of TUBB4A ( C ).

Techniques Used:

The co-expressed genes of  TUBB4A  commonly appeared in UALCAN database and GEPIA database.
Figure Legend Snippet: The co-expressed genes of TUBB4A commonly appeared in UALCAN database and GEPIA database.

Techniques Used:

Correlation analysis. The expression of TUBB4A in SKCM was positively correlated with the expression of T cell CD4+ Th1 and T cell NK, respectively, by XCELL immune infiltration analysis.
Figure Legend Snippet: Correlation analysis. The expression of TUBB4A in SKCM was positively correlated with the expression of T cell CD4+ Th1 and T cell NK, respectively, by XCELL immune infiltration analysis.

Techniques Used: Expressing

Associations with Clinicopathologic Characteristics in SKCM Patients Using Cox Regression. C-index: 0.725(0.699-0.750).
Figure Legend Snippet: Associations with Clinicopathologic Characteristics in SKCM Patients Using Cox Regression. C-index: 0.725(0.699-0.750).

Techniques Used:

Diagnostic Value of TUBB4A Expression in SKCM. Forest plot of the multivariate Cox regression analysis in SKCM ( A ). A receiver operating characteristic (ROC) curve in SKCM between tumor and normal samples ( B ). A nomogram for predicting the probability of patients with 1-, 3- and 5-year overall survival (OS) ( C ). Calibration curve of the nomogram in 1-year,3-year and 5-year ( D-F ).
Figure Legend Snippet: Diagnostic Value of TUBB4A Expression in SKCM. Forest plot of the multivariate Cox regression analysis in SKCM ( A ). A receiver operating characteristic (ROC) curve in SKCM between tumor and normal samples ( B ). A nomogram for predicting the probability of patients with 1-, 3- and 5-year overall survival (OS) ( C ). Calibration curve of the nomogram in 1-year,3-year and 5-year ( D-F ).

Techniques Used: Diagnostic Assay, Expressing

Related Articles

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Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma
Article Snippet: .. TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database. ..



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Human Protein Atlas tubb4a protein
The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.
Tubb4a Protein, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/tubb4a+protein/immunohistochemistry+of+tubb4a+in+skcm+and+normal+skin+tissues/pmc10173467-237-0-21
Average 90 stars, based on 1 article reviews
tubb4a protein - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

Image Search Results


The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques:

Univariate and Multivariate Cox analysis of 13 candidate genes.

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: Univariate and Multivariate Cox analysis of 13 candidate genes.

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques:

Expression levels of DLL3 and TUBB4A ( A,B ),“*” represents “p-value < 0.05”;Disease Free Survival(DFS) ( C,D ); Progress Free Interval (PFI) ( E,F ); Disease Specific Survival (DSS) ( G,H ).

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: Expression levels of DLL3 and TUBB4A ( A,B ),“*” represents “p-value < 0.05”;Disease Free Survival(DFS) ( C,D ); Progress Free Interval (PFI) ( E,F ); Disease Specific Survival (DSS) ( G,H ).

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques: Expressing, Significance Assay

Immunohistochemistry images of TUBB4A in SKCM tissues and normal skin tissues from Human Protein Atlas ( A ). The results of RT-qPCR of TUBB4A expression levels in skin cutaneous melanoma cell lines ( B ). ***, **, and * represent significant differences between skin cutaneous melanoma cell lines and human primary normal skin melanocytes, respectively (P<0.001, P<0.01, P<0.05).

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: Immunohistochemistry images of TUBB4A in SKCM tissues and normal skin tissues from Human Protein Atlas ( A ). The results of RT-qPCR of TUBB4A expression levels in skin cutaneous melanoma cell lines ( B ). ***, **, and * represent significant differences between skin cutaneous melanoma cell lines and human primary normal skin melanocytes, respectively (P<0.001, P<0.01, P<0.05).

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques: Immunohistochemistry, Quantitative RT-PCR, Expressing

Prediction of miRNAs binding to  TUBB4A.

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: Prediction of miRNAs binding to TUBB4A.

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques: Binding Assay

Upstream potential miRNAs predicted to bind to TUBB4A. The miRNA-TUBB4A network ( A ). Overall survival (OS) of miRNAs in TCGA-SKCM cohort ( B ). The expression of TUBB4A and hsa-let-7b-5p in SKCM was negatively correlated ( C ). The expression of TUBB4A and hsa-miR-423-5p in SKCM was positively correlated ( D ).

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: Upstream potential miRNAs predicted to bind to TUBB4A. The miRNA-TUBB4A network ( A ). Overall survival (OS) of miRNAs in TCGA-SKCM cohort ( B ). The expression of TUBB4A and hsa-let-7b-5p in SKCM was negatively correlated ( C ). The expression of TUBB4A and hsa-miR-423-5p in SKCM was positively correlated ( D ).

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques: Expressing

The upstream lncRNAs of hsa-let-7b-5p in SKCM. The lncRNAs-hsa-let-7b-5p network ( A ). The expression levels of SNHG16 in skin cutaneous melanoma compared with TCGA normal and GTEx data controls ( B ), “*” represents “p-value < 0.05”. The expression of hsa-let-7b-5p and SNHG16 in SKCM was negatively correlated ( C ). The expression of TUBB4A and SNHG16 in SKCM was positively correlated ( D ).

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: The upstream lncRNAs of hsa-let-7b-5p in SKCM. The lncRNAs-hsa-let-7b-5p network ( A ). The expression levels of SNHG16 in skin cutaneous melanoma compared with TCGA normal and GTEx data controls ( B ), “*” represents “p-value < 0.05”. The expression of hsa-let-7b-5p and SNHG16 in SKCM was negatively correlated ( C ). The expression of TUBB4A and SNHG16 in SKCM was positively correlated ( D ).

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques: Expressing, Significance Assay

The co-expressed genes of TUBB4A in SKCM through UALCAN and GEPIA database ( A ). The top 8 enriched in biological process (BP), cellular component (CC), molecular function (MF)items for the co-expressed genes of TUBB4A ( B ). The top 8 enriched in KEGG for the co-expressed genes of TUBB4A ( C ).

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: The co-expressed genes of TUBB4A in SKCM through UALCAN and GEPIA database ( A ). The top 8 enriched in biological process (BP), cellular component (CC), molecular function (MF)items for the co-expressed genes of TUBB4A ( B ). The top 8 enriched in KEGG for the co-expressed genes of TUBB4A ( C ).

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques:

The co-expressed genes of  TUBB4A  commonly appeared in UALCAN database and GEPIA database.

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: The co-expressed genes of TUBB4A commonly appeared in UALCAN database and GEPIA database.

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques:

Correlation analysis. The expression of TUBB4A in SKCM was positively correlated with the expression of T cell CD4+ Th1 and T cell NK, respectively, by XCELL immune infiltration analysis.

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: Correlation analysis. The expression of TUBB4A in SKCM was positively correlated with the expression of T cell CD4+ Th1 and T cell NK, respectively, by XCELL immune infiltration analysis.

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques: Expressing

Associations with Clinicopathologic Characteristics in SKCM Patients Using Cox Regression. C-index: 0.725(0.699-0.750).

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: Associations with Clinicopathologic Characteristics in SKCM Patients Using Cox Regression. C-index: 0.725(0.699-0.750).

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques:

Diagnostic Value of TUBB4A Expression in SKCM. Forest plot of the multivariate Cox regression analysis in SKCM ( A ). A receiver operating characteristic (ROC) curve in SKCM between tumor and normal samples ( B ). A nomogram for predicting the probability of patients with 1-, 3- and 5-year overall survival (OS) ( C ). Calibration curve of the nomogram in 1-year,3-year and 5-year ( D-F ).

Journal: Current Protein & Peptide Science

Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

doi: 10.2174/1389201023666220928120902

Figure Lengend Snippet: Diagnostic Value of TUBB4A Expression in SKCM. Forest plot of the multivariate Cox regression analysis in SKCM ( A ). A receiver operating characteristic (ROC) curve in SKCM between tumor and normal samples ( B ). A nomogram for predicting the probability of patients with 1-, 3- and 5-year overall survival (OS) ( C ). Calibration curve of the nomogram in 1-year,3-year and 5-year ( D-F ).

Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

Techniques: Diagnostic Assay, Expressing